Veröffentlichungen zur Anwendung der konfokalen Endomikroskopie (CLE) bei kranialen Eingriffen
Auflistung wissenschaftlicher Veröffentlichungen zum Stellenwert der CLE für die intraoperativen Beurteilung der Gewebefeinstruktur
In dieser Übersicht stellt ZEISS klinische Fachbeiträge zur Anwendung von konfokaler Endomikroskopie (CLE) bei kranialen Eingriffen zur Verfügung, mit Fokus auf die Nutzung zur Visualisierung der Gewebefeinstruktur. Zu den weiteren themenrelevanten Aspekten, die darüber hinaus beleuchtet werden, zählen u. a. technologische Fragen, Möglichkeiten zur Workflow-Optimierung und wirtschaftliche Auswirkungen. Auf diese Weise möchten wir Ihnen den Zugang zu weiterführenden Informationen ermöglichen und Fachwissen mit Ihnen teilen.
Jede Veröffentlichung beruht auf der fachlichen Meinung oder den Studienergebnissen des jeweiligen Autors. Sie spiegelt nicht zwingend die Auffassung der Carl Zeiss Meditec AG wider und stimmt nicht unbedingt mit der klinischen Bewertung oder Zweckbestimmung unserer Medizinprodukte überein. Die klinische Anwendbarkeit der einzelnen Publikationen ist daher durch den ausführenden Arzt sorgfältig zu prüfen.
Neuro-Indikationen
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2024 May
Intraoperative in vivo confocal endomicroscopy of the glioma margin: performance assessment of image interpretation by neurosurgeon users
Frontiers in Oncology
Xu Y, On TJ, Abramov I, Restelli F, Belykh E, Mathis AM, Schlegel J, Hewer E, Pollo B, Maragkou T, Quint K, Porter RW, Smith KA, Preul MC
2024 Jan
Fluorescein-stained confocal laser endomicroscopy versus conventional frozen section for intraoperative histopathological assessment of intracranial tumors
Neuro-Oncology
Wagner A, Brielmaier MC, Kampf C, Baumgart L, Aftahy AK, Meyer HS, Kehl V, Höhne J, Schebesch KM, Schmidt NO, Zoubaa S, Riemenschneider MJ, Ratliff M, Enders F, von Deimling A, Liesche-Starnecker F, Delbridge C, Schlegel J, Meyer B, Gempt J
2023 Sep
Intraoperative confocal laser endomicroscopy for interpretation of a sellar hemangioblastoma: illustrative case
Journal of Neurosurgery
Abramov I, Furey CG, Xu Y, Eschbacher JM, Smith KA, Preul MC
2023 Aug
Intraoperative in vivo confocal laser endomicroscopy imaging at glioma margins: can we detect tumor infiltration?
Journal of Neurosurgery
Xu Y, Mathis AM, Pollo B, Schlegel J, Maragkou T, Seidel K, Schucht P, Smith KA, Porter RW, Raabe A, Little AS, Sanai N, Agbanyim DC, Martirosyan NL, Eschbacher JM, Quint K, Preul MC, Hewer E
2022 Sep
Introduction of In Vivo Confocal Laser Endomicroscopy and Real-Time Telepathology for Remote Intraoperative Neurosurgery-Pathology Consultation
Operative Neurosurgery
Park MT, Abramov I, Gooldy TC, Smith KA, Porter RW, Little AS, Lawton MT, Eschbacher JM, Preul MC
2022 Jun
Real-time intraoperative surgical telepathology using confocal laser endomicroscopy
Neurosurgical Focus
Abramov I, Park MT, Gooldy TC, Xu Y, Lawton MT, Little AS, Porter RW, Smith KA, Eschbacher JM, Preul MC
2022
A new study protocol for in vivo assessment of tumor diagnosis and microscopic tumor infiltration at the resection cavity in Central Nervous System tumors by a new miniature confocal endomicroscope (CONVIVO system)
Journal of Neurosurgical Sciences
Restelli F, Mazzapicchi E, Pollo B, Falco J, Bonomo G, La Corte E, Broggi M, Schiariti M, Di Meco F, Ferroli P, Tramacere I, Acerbi F
2022
Intraoperative confocal laser endomicroscopy: prospective in vivo feasibility study of a clinical-grade system for brain tumors
Journal of Neurosurgery
Abramov I, Park MT, Belykh E, Dru AB, Xu Y, Gooldy TC, Scherschinski L, Farber SH, Little AS, Porter RW, Smith KA, Lawton MT, Eschbacher JM, Preul MC
2021
Intraoperative imaging of brain tumors with fluorescein: confocal laser endomicroscopy in neurosurgery. Clinical and user experience
Neurosurgical Focus FOC
Höhne J, Schebesch KM, Zoubaa S, Proescholdt M, Riemenschneider MJ, Schmidt NO
2020
Ex Vivo Fluorescein-Assisted Confocal Laser Endomicroscopy (CONVIVO® System) in Patients With Glioblastoma: Results From a Prospective Study
Frontiers in Oncology
Acerbi F, Pollo B, De Laurentis C, Restelli F, Falco J, Vetrano IG, Broggi M, Schiariti M, Tramacere I, Ferroli P, DiMeco F
2020
Confocal laser endomicroscopy assessment of pituitary tumor microstructure: A feasibility study
Journal of Clinical Medicine
Belykh E, Ngo B, Farhadi DS, Zhao X, Mooney MA, White WL, Daniels JK, Little AS, Eschbacher JM, Preul MC
2020
Intraoperative Confocal Laser Endomicroscopy Ex Vivo Examination of Tissue Microstructure During Fluorescence-Guided Brain Tumor Surgery
Frontiers in Oncology
Belykh E, Zhao X, Ngo B, Farhadi DS, Byvaltsev VA, Eschbacher JM, Nakaji P, Preul MC
2018
Confocal scanning microscopy provides rapid, detailed intraoperative histological assessment of brain neoplasms: Experience with 106 cases
Clinical Neurology and Neurosurgery
Martirosyan NL, Georges J, Eschbacher JM, Belykh E, Carotenuto A, Spetzler RF, Nakaji P, Preul MC
2017
Confocal Laser Endomicroscopy in Neurosurgery—An Alternative to Instantaneous Sections?
World Neurosurgery
Breuskin D, Szczygielski J, Urbschat S, Kim YJ, Oertel J
2016
Prospective evaluation of the utility of intraoperative confocal laser endomicroscopy in patients with brain neoplasms using fluorescein sodium: Experience with 74 cases
Neurosurgical Focus
Martirosyan NL, Eschbacher JM, Yashar M, Turner JD, Belykh E, Spetzler RF, Nakaji P, Preul MC
2016
Intraoperative Probe-Based Confocal Laser Endomicroscopy in Surgery and Stereotactic Biopsy of Low-Grade and High-Grade Gliomas: A Feasibility Study in Humans
Neurosurgery
Pavlov V, Meyronet D, Meyer-Bisch V, Armoiry X, Pikul B, Dumot C, Beuriat PA, Signorelli F, Guyotat J
2015
Confocal laser endomicroscopy for real-time histomorphological diagnosis: Our clinical experience with 150 brain and spinal tumor cases
Neurosurgery
Charalampaki P, Javed M, Daali S, Heiroth HJ, Igressa A, Weber F
2012
In vivo intraoperative confocal microscopy for real-time histopathological imaging of brain tumors: Clinical article
Journal of Neurosurgery
Eschbacher J, Martirosyan NL, Nakaji P, Sanai N, Preul MC, Smith KA, Coons SW, Spetzler RF
2011
Intraoperative confocal microscopy in the visualization of 5-aminolevulinic acid fluorescence in low-grade gliomas: Clinical article
Journal of Neurosurgery
Sanai N, Snyder LA, Honea NJ, Coons SW, Eschbacher JM, Smith KA, Spetzler RF
2010
Confocal neurolasermicroscopy in human brain – perspectives for neurosurgery on a cellular level (including additional Comments to this article)
Zentralblatt für Neurochirurgie
Schlosser HG, Suess O, Vajkoczy P, Van Landeghem FK, Zeitz M, Bojarski C
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Jahr
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2021
Visualization of brain microvasculature and blood flow in vivo: Feasibility study using confocal laser endomicroscopy
Microcirculation
Belykh E, Zhao X, Ngo B, Farhadi DS, Kindelin A, Ahmad S, Martirosyan NL, Lawton MT, Preul MC
2018
Diagnostic Accuracy of a Confocal Laser Endomicroscope for InVivo Differentiation Between Normal Injured And Tumor Tissue During Fluorescein-Guided Glioma Resection: Laboratory Investigation
World Neurosurgery
Belykh E, Miller EJ, Patel AA, Yazdanabadi MI, Martirosyan NL, Yağmurlu K, Bozkurt B, Byvaltsev VA, Eschbacher JM, Nakaji P, Preul MC
2013
Miniaturized handheld confocal microscopy identifies focal brain invasion in a mouse model of aggressive meningioma
Brain Pathology
Peyre M, Clermont-Taranchon E, Stemmer-Rachamimov A, Kalamarides M
2012
Confocal laser endomicroscopy for diagnosis and histomorphologic imaging of brain tumors in vivo
PLOS ONE
Foersch S, Heimann A, Ayyad A, Spoden GA, Florin L, Mpoukouvalas K, Kiesslich R, Kempski O, Goetz M, Charalampaki P
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2022
Characterization of ex vivo and in vivo intraoperative neurosurgical confocal laser endomicroscopy imaging
Frontiers in Oncology
Xu Y, Abramov I, Belykh E, Mignucci-Jiménez G, Park MT, Eschbacher JM, Preul MC
2021
Redosing of Fluorescein Sodium Improves Image Interpretation During Intraoperative Ex Vivo Confocal Laser Endomicroscopy of Brain Tumors
Frontiers in Oncology
Abramov I, Dru AB, Belykh E, Park MT, Bardonova L, Preul MC
2021
High-Dose Fluorescein Reveals Unusual Confocal Endomicroscope Imaging of Low-Grade Glioma
Frontiers in Neurology
Belykh E, Onaka NR, Zhao X, Abramov I, Eschbacher JM, Nakaji P, Preul MC
2021
Fluorescence-Guided Surgery: A Review on Timing and Use in Brain Tumor Surgery
Frontiers in Neurology
Schupper AJ, Rao M, Mohammadi N, Baron R, Lee JY, Acerbi F, Hadjipanayis CG
2020
Blood-Brain Barrier, Blood-Brain Tumor Barrier, and Fluorescence-Guided Neurosurgical Oncology: Delivering Optical Labels to Brain Tumors
Frontiers in Oncology
Belykh E, Shaffer KV, Lin C, Byvaltsev VA, Preul MC, Chen L
2019
Progress in Confocal Laser Endomicroscopy for Neurosurgery and Technical Nuances for Brain Tumor Imaging With Fluorescein
Frontiers in Oncology
Belykh E, Miller EJ, Carotenuto A, Patel AA, Cavallo C, Martirosyan NL, Healey DR, Byvaltsev VA, Scheck AC, Lawton MT, Eschbacher JM, Nakaji P, Preul MC
2018
Dual-labeling with 5-aminolevulinic acid and fluorescein for fluorescence-guided resection of high-grade gliomas: Technical note
Journal of Neurosurgery
Molina ES, Wölfer J, Ewelt C, Ehrhardt A, Brokinkel B, Stummer W
2018
Probe-based three-dimensional confocal laser endomicroscopy of brain tumors: Technical note
Cancer Management and Research
Belykh E, Patel AA, Miller EJ, Bozkurt B, Yağmurlu K, Woolf EC, Scheck AC, Eschbacher JM, Nakaji P, Preul MC
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Jahr
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2022 Oct
Confocal laser imaging in neurosurgery: A comprehensive review of sodium fluorescein-based CONVIVO preclinical and clinical applications
Frontiers in Oncology
Restelli F, Mathis AM, Höhne J, Mazzapicchi E, Acerbi F, Pollo B, Quint K
2021
Confocal laser microscopy in neurosurgery: State of the art of actual clinical applications
Journal of Clinical Medicine
Restelli F, Pollo B, Vetrano IG, Cabras S, Broggi M, Schiariti M, Falco J, de Laurentis C, Raccuia G, Ferroli P, Acerbi F
2018
Utilization of intraoperative confocal laser endomicroscopy in brain tumor surgery
Journal of Neurosurgical Sciences
Belykh E, Cavallo C, Gandhi S, Zhao X, Veljanoski D, Yazdanabadi MI, Martirosyan NL, Byvaltsev VA, Eschbacher J, Preul MC, Nakaji P
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2022 Nov
Intraoperative confocal laser endomicroscopy for brain tumors - potential and challenges from a neuropathological perspective
Free Neuropathology
Maragkou T, Quint K, Pollo B, Hewer E
2022
Real-time intraoperative surgical telepathology using confocal laser endomicroscopy
Journal of Neurosurgery
Abramov I, Park MT, Gooldy TC, Xu Y, Lawton MT, Little AS, Porter RW, Smith KA, Eschbacher JM, Preul MC
2021
Socio-organizational impact of confocal laser endomicroscopy in neurosurgery and neuropathology: Results from a process analysis and expert survey
Diagnostics
Fotteler ML, Liesche-Starnecker F, Brielmaier MC, Schobel J, Gempt J, Schlegel J, Swoboda W
2000
Accuracy, Utility, and Cost of Frozen Section Margins in Head and Neck Cancer Surgery
The Laryngoscope
DiNardo LJ, Lin J, Karageorge LS, Powers CN
2019
In Vivo and Ex Vivo Microscopy: Moving Toward the Integration of Optical Imaging Technologies Into Pathology Practice
Archives of Pathology and Laboratory Medicine
Wells WA, Thrall M, Sorokina A, Fine J, Krishnamurthy S, Haroon A, Rao B, Shevchuk MM, Wolfsen HC, Tearney GJ, Hariri LP
2019
Clinical Benefits of Combining Different Visualization Modalities in Neurosurgery
Frontiers in Surgery
Schebesch KM, Rosengarth K, Brawanski A, Proescholdt M, Wendl C, Höhne J, Ott C, Lamecker H, Doenitz C
2019
In vivo and ex vivo microscopy: A business plan to justify the introduction of similar emerging technologies into pathology practice
Archives of Pathology and Laboratory Medicine
Wells WA, Harhen MT, Thrall MJ, Shevchuk MM, Tearney GJ, Hariri LP
2019
Toward Quantitative Neurosurgical Guidance With High-Resolution Microscopy of 5-Aminolevulinic Acid-Induced Protoporphyrin IX
Frontiers in Oncology
Wei L, Fujita Y, Sanai N, Liu JT
Sonstige Indikationen
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Jahr
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2021
Fluorescein-Guided Panendoscopy for Head and Neck Cancer Using Handheld Probe-Based Confocal Laser Endomicroscopy: A Pilot Study
Frontiers in Oncology
Dittberner A, Ziadat R, Hoffmann F, Pertzborn D, Gassler N, Guntinas-Lichius O
2021
Confocal laser endomicroscopy of head and neck squamous cell carcinoma: a systematic review
Laryngo-Rhino-Otologie
Sievert M, Auberville M, Oetter N, Stelzle F, Maier A, Mantsopoulos K, Iro H, Goncalves M
2021
Intraoperative free margins assessment of oropharyngeal squamous cell carcinoma with confocal laser endomicroscopy: a pilot study
European Archives of Oto-Rhino-Laryngology
Sievert M, Stelzle F, Aubreville M, Mueller SK, Eckstein M, Oetter N, Maier A, Mantsopoulos K, Iro H, Goncalves M
2019
Probe-based confocal laser endomicroscopy for diagnosis of nasopharyngeal carcinoma in vivo
The Laryngoscope
Wu L, Yu H, Zhou R, Luo J, Zhao J, Li Y, Wang K, Wang Y, Li H
2019
Probe-based confocal laser endomicroscopy in detecting malignant lesions of vocal folds
Acta Otorhinolaryngologica Italica
Goncalves M, Aubreville M, Mueller SK, Sievert M, Maier A, Iro H, Bohr C
2017
Value of confocal laser endomicroscopy in the diagnosis of vocal cord lesions
European review for medical and pharmacological sciences
Goncalves M, Iro H, Dittberner A, Agaimy A, Bohr C
2016
Evaluation of confocal laser endomicroscopy as an aid to differentiate primary flat lesions of the larynx: A prospective clinical study
Head & Neck
Volgger V, Girschick S, Ihrler S, Englhard AS, Stepp H, Betz CS
2016
Noninvasive histological imaging of head and neck squamous cell carcinomas using confocal laser endomicroscopy
European Archives of Oto-Rhino-Laryngology
Linxweiler M, Kadah BA, Bozzato A, Bozzato V, Hasenfus A, Kim YJ, Wagner M, Igressa A, Schick B, Charalampaki P
2012
Systematic intraoperative application of confocal endomicroscopy for early detection and resection of squamous cell carcinoma of the head and neck: A preliminary report
Archives of Otolaryngology - Head and Neck Surgery
Pogorzelski B, Hanenkamp U, Goetz M, Kiesslich R, Gosepath J
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Jahr
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2015
Confocal laser endomicroscopy in breast surgery: A pilot study
BMC Cancer
De Palma GD, Esposito D, Luglio G, Limite G, Accurso A, Sollazzo V, Maione F, Cassese G, Siciliano S, Gennarelli N, Ilardi G, Paternoster M, Giglio MC, Forestieri P
2015
Imaging breast cancer morphology using probe-based confocal laser endomicroscopy: towards a real-time intraoperative imaging tool for cavity scanning
Breast Cancer Research and Treatment
Chang TP, Leff DR, Shousha S, Hadjiminas DJ, Ramakrishnan R, Hughes MR, Yang GZ, Darzi A
2014
Fluorescence confocal microscopy for pathologists
Modern Pathology
Ragazzi M, Piana S, Longo C, Castagnetti F, Foroni M, Ferrari G, Gardini G, Pellacani G
Translationale Forschung und Technologie
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Jahr
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2021
Deep Neural Network for Differentiation of Brain Tumor Tissue Displayed by Confocal Laser Endomicroscopy
Frontiers in Oncology
Ziebart A, Stadniczuk D, Roos V, Ratliff M, von Deimling A, Hänggi D, Enders F
2018
Context aware decision support in neurosurgical oncology based on an efficient classification of endomicroscopic data
International Journal of Computer Assisted Radiology and Surgery
Li Y, Charalampaki P, Liu Y, Yang GZ, Giannarou S
2018
Convolutional neural networks: Ensemble modeling, fine-tuning and unsupervised semantic localization for neurosurgical CLE images
Journal of Visual Communication and Image Representation
Izadyyazdanabadi M, Belykh E, Mooney M, Martirosyan N, Eschbacher J, Nakaji P, Preul MC, Yang Y
2018
Weakly-supervised learning-based feature localization for confocal laser endomicroscopy glioma images
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Izadyyazdanabadi M, Belykh E, Cavallo C, Zhao X, Gandhi S, Moreira LB, Eschbacher J, Nakaji P, Preul MC, Yang Y
2018
Prospects for theranostics in neurosurgical imaging: Empowering confocal laser endomicroscopy diagnostics via deep learning
Frontiers in Oncology
Izadyyazdanabadi M, Belykh E, Mooney MA, Eschbacher JM, Nakaji P, Yang Y, Preul MC
2016
Automatic Tissue Differentiation Based on Confocal Endomicroscopic Images for Intraoperative Guidance in Neurosurgery
BioMed Research International
Kamen A, Sun S, Wan S, Kluckner S, Chen T, Gigler AM, Simon E, Fleischer M, Javed M, Daali S, Igressa A, Charalampaki P
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