ZEISS AT LISA tri family

Author: Lenton, L.; Vision Eye Institute Clinic

A clinical investigation analyzing the performance of adults with ZEISS AT LISA tri in a realistic flight simulator found that AT LISA tri patients did not experience constraints from a vision perspective in terms of ability to perform tasks in a flight simulator such as simulated landing runs in both daytime and night-time conditions.

No of patients: 13
Follow up time: n/a

Reference: Lenton, L. (2018). Visual performance in a flight simulator: multifocal intraocular lenses in pilots. BMJ Open Ophthalmology.

Author: Yang, Y. et al.;  Department of Ophthalmology, Peking University Third Hospital

At 3 months postoperatively, the cohort reported a spectacle independence rate of 100%.

No. of patients: 26
Follow Up: 1 week, 1M, 3M

Reference: Yang, Y. et al.(2018). Clinical outcomes following trifocal diffractive intraocular lens implantation for age-related cataract in China. Clinical Ophthalmology. Volume 2018:12 Pages 1317—1324.

Author: Mojzis, P. et al.;  Premium Clinic Teplice

The study analyzed AT LISA tri’s performance in terms of contrast sensitivity and found that patient outcomes are in the normal range, both in photopic as well as mesopic conditions.

No. of Patients: 60

Reference: Mojzis, P. et al. (2015). Visual Outcomes of a new toric trifocal diffractive intraocular lens. JCRS, 41(12): 2695-2706

Authors: Kretz, F. et al.;  Augenklinik Ahaus-Raesfeld-Rheine

All patients (100%) were satisfied in terms of their ability to read, their intermediate and distance vision, their quality of vision at all distances, and their independence of spectacles for performing their daily activities and for the use of computer.

No. of patients: 38
Follow Up: 3M

Reference: Kretz, F. et al. (2015). Clinical Outcomes after Binocular Implantation of a New Trifocal Diffractive Intraocular Lens. Journal of Refractive Surgery. 2015;31(8):504-510.

Authors: Ganesh, S. et al.;  Nethradhama Superspeciality Eye Hospital

Even under mesopic conditions patients with ZEISS AT LISA tri benefit from continuously high levels of visual acuity better than 0.1logMAR over a defocus up to -3 D, equaling a viewing distance of 33 cm. Spectacle independence rate was at 100%.
Study

No. of patients: 25
Follow Up: 12M

Reference: Ganesh, S. et al. (2017). Long-term visual outcomes and patient satisfaction following bilateral implantation of trifocal intraocular lenses. Clinical Ophthalmology, II: 1453-1459

Authors: Farideh, D., et al.;  Eye Research Center, Tehran University of Medical Sciences

Analyzing outcomes for AT LISA tri toric implantation in keratoconus patients, investigators found that the IOL provided appropriate distance, near and intermediate visual results. Prediction of the refractive results and optical performances were good.

No. of patients & Follow Up: 5

Reference: Farideh, D. et al. (2017). Clinical outcomes of new toric trifocal diffractive intraocular lens in patients with cataract and stable keratoconus: Six months follow-up. Medicine. Mar 2017; 96(12):e6340.

Authors: Mencucci, R. et al.;  Department of Surgery and Translational Medicine, Eye Clinic, University of Florence

Analysis of patient satisfaction with AT LISA tri confirmed good feedback at all three distances.

No. of patients: 21
Follow Up: 3M

Reference: Mencucci, R. et al. (2017). Visual performance, reading ability and patient satisfaction after implantation of a diffractive trifocal intraocular lens. Clinical Ophthalmology. Volume 2017:11 Pages 1987—1993.

Authors: Velasco-Barona, C et al.;  Anterior Segment Surgery Department, Asociación para Evitar la Ceguera

The study found “no associations between angle k distance and postoperative visual acuity regardless of the angle k magnitude”.

No. of patients & Follow Up: 20

Reference: Velasco-Barona, C. et al. (2019). Influence of Angle κ and Higher-Order Aberrations on Visual Quality Employing Two Diffractive Trifocal IOLs. Journal of Ophthalmology. Volume 2019.

Authors: Gundersen, K. and Potvin, R.;  IFocus Øyeklinikk

Gundersen and Potvin highlight superiority of bilateral implantation of AT LISA tri vs mono-vision with competitor bifocal IOLs, in particular at intermediate distances where a statistically significant better VA outcome was found from 2m to 67cm.

No. of patients & Follow up time: 55 (25 patients trifocal cohort, 30 patients bifocal cohort)

Reference: Gundersen, K. and Potvin, R. (2016). Comparison of visual outcomes and subjective visual quality after bilateral implantation of a diffractive trifocal intraocular lens and blended implantation of apodized diffractive bifocal intraocular lenses. Clinical Ophthalmology; 2016 Mar 17;10:805-811.

Authors: Marques, E. and Ferreira, T.;  Cruz Vermelha Hospital

100% of AT LISA tri patients in this study achieved spectacle independence.

No. of patients: 30
Follow up time: 3M

Reference: Marques, E. and Ferreira, T. (2015). Comparison of visual outcomes of 2 diffractive trifocal intraocular lenses. JCRS. Volume 41, Issue 2, February 2015, Pages 354-363.

Authors: Filip, M. et al.;  AmaOptimex Eye Clinic

“In the overall estimation, 90,19% of the patients were happy, in 7,84% of cases, the result was satisfactory and 1,96% were unhappy due to miodesopsias.”

No. of patients: 102

Reference: Filip, M. et al. (2016). Refractive results with the use of AT.Lisa intraocular lens (2008-2015). Romanian Journal of Ophthalmology, Volume 60, Issue 1, January-March 2016. pp:18-20.

Authors:  Almulhim, A. et al.;  Department of Ophthalmology, Aljouf University

Patients achieved very high spectacle independence at all three distances, with distance reaching 95%, intermediate 98% and near 100%.

No. of patients: 41
Follow up: 3M

Reference: Almulhim, A. et al., (2018). Visual outcomes and patient satisfaction after bilateral implantation of a new trifocal diffractive intraocular lens. Saudi Journal of Ophthalmology. Volume 32, 310–317.

Authors: Song, J.E. et al.;  Department of Ophthalmology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

Patients with combined implantation of AT LARA (EDoF IOL) and AT LISA tri (trifocal IOL) achieved better visual acuity results at intermediate and near distances without compromising far distance vision compared to the monocular outcomes of each IOL. The combined implantation of an EDoF and a trifocal IOL can be a viable option for patients with high demands for spectacle independence in their daily life with minimal optical phenomena.

No. of patients: 25
Follow-up: 6M

Reference: Song, J.E. et al. (2021): Clinical Outcomes of Combined Implantation of an Extended Depth of Focus IOL and a Trifocal IOL in a Korean Population,  Journal of Ophthalmology.

Authors: Bilbao-Calabuig, R. et al.;  Clinica Baviera Madrid, lnstituto Oftalmologico Europeo

In a comparative study with >4.000 patients per group, higher patient satisfaction was found with AT LISA tri than with FineVision.

No. of patients: 2141
Follow up time: 3M

Reference: Bilbao-Calabuig, R. et al. (2017) Visual Outcomes Following Bilateral Implantation of Two Diffractive Trifocal IOLs in 10 084 eyes. Ophthalmology 2017;179:55-66.

Authors:  Law, E. et al.;  BMI Southend Private Hospital

AT LISA tri provides excellent uncorrected distance, intermediate, and near visual outcomes. Even for small print activities such as reading labels, no patient experienced tasks as very difficult.

No. of patients: 30
Follow up time: 1M, 3M & 6M

Reference: Law, E. et al. (2013). Clinical outcomes with a new trifocal intraocular lens. European Journal of Ophthalmology. Volume: 24 issue: 4, page(s): 501-508