Press Release

ZEISS arivis software enhances custom microscopy image analysis

Introducing ZEISS arivis Pro 4.2

19 June 2024

Offers users the freedom to select the most suitable image analysis method for their needs
New release includes enhanced AI-driven tools, 3D analysis capabilities, and large dataset handling
Unprecedented flexibility to tailor microscopy image analysis workflows to answer research questions

Jena, Germany | 19 June 2024 | ZEISS Research Microscopy Solutions

ZEISS today unveiled arivis Pro version 4.2, empowering researchers with unprecedented flexibility to tailor microscopy image analysis to their unique needs. This major release introduces advanced AI-powered segmentation tools, enhanced 3D analysis capabilities, and seamless handling of massive datasets – a universal solution optimized for any imaging workflow.

ZEISS
The figure displays a cross-sectional view of an intestinal gut organoid captured at 20X magnification on ZEISS Celldiscoverer 7 and segmented using ZEISS arivis Pro image analysis software. The image highlights outer cell layer nuclei in pink and the inner luminal nuclei in yellow.
3D volume rendering of segmented mouse muscle ultrastructure overlaid on the original EM data. The rendering visualizes the segmented components of the muscle tissue, including filaments (green), capillary (yellow), myofibrils (blue), mitochondria (cyan), and sarcoplasmic reticulum (pink), in their native 3D context within the EM volume.

The power of customization

“Our goal with arivis Pro 4.2 is to put the power of customization directly into the user’s hands,” says Dr. Sreenivas Bhattiprolu, Head of Digital Solutions at ZEISS. “Whether working with small datasets or incredibly large 3D volumes, researchers can now leverage the most appropriate tools for their specific analysis requirements.”

Advanced AI-powered segmentation tools

A cornerstone of the new version is the integration of cutting-edge instance segmentation models powered by deep learning. Trained on the ZEISS arivis Cloud, these models enable users to precisely segment individual objects within images using AI – without any coding expertise required. Additionally, pre-trained models from the open-source Cellpose library enable users to segment cells and nuclei in most images effortlessly.

“In microscopy, no two datasets are alike,” explains Dr. Bhattiprolu. “Some demand traditional segmentation methods, while others benefit from AI-driven approaches. With arivis Pro 4.2, we empower researchers to choose the ideal techniques for each unique scenario.”

Enhanced 3D analysis capabilities and seamless handling of massive datasets

As researchers increasingly adopt 3D imaging methods to gain more comprehensive insights, especially in areas like drug discovery, the need for powerful 3D analysis tools continues to grow. With arivis Pro 4.2, ZEISS delivers a robust solution tailored for these evolving demands. The new version allows users to seamlessly load, visualize, and extract rich insights from massive 3D datasets containing a vast number of objects, enabling unprecedented exploration of complex 3D volumes at scale.

The arivis Pro 4.2 release underscores ZEISS’s commitment to delivering cutting-edge, user-centric solutions that accelerate scientific discovery.

Further information

ZEISS arivis Pro 4.2

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Press Contact Vybhav Sinha ZEISS Research Microscopy Solutions

About ZEISS

ZEISS is an internationally leading technology enterprise operating in the fields of optics and optoelectronics. In the previous fiscal year, the ZEISS Group generated annual revenue totaling 10 billion euros in its four segments Semiconductor Manufacturing Technology, Industrial Quality & Research, Medical Technology and Consumer Markets (status: 30 September 2023).

For its customers, ZEISS develops, produces and distributes highly innovative solutions for industrial metrology and quality assurance, microscopy solutions for the life sciences and materials research, and medical technology solutions for diagnostics and treatment in ophthalmology and microsurgery. The name ZEISS is also synonymous with the world's leading lithography optics, which are used by the chip industry to manufacture semiconductor components. There is global demand for trendsetting ZEISS brand products such as eyeglass lenses, camera lenses and binoculars.

With a portfolio aligned with future growth areas like digitalization, healthcare and Smart Production and a strong brand, ZEISS is shaping the future of technology and constantly advancing the world of optics and related fields with its solutions. The company's significant, sustainable investments in research and development lay the foundation for the success and continued expansion of ZEISS' technology and market leadership. ZEISS invests 15 percent of its revenue in research and development – this high level of expenditure has a long tradition at ZEISS and is also an investment in the future.

With over 44,000 employees, ZEISS is active globally in around 50 countries with more than 60 sales and service locations, 35 research and development facilities, and 35 production facilities worldwide (status: 31 March 2024). Founded in 1846 in Jena, the company is headquartered in Oberkochen, Germany. The Carl Zeiss Foundation, one of the largest foundations in Germany committed to the promotion of science, is the sole owner of the holding company, Carl Zeiss AG.

Further information at www.zeiss.com

ZEISS Research Microscopy Solutions

ZEISS Research Microscopy Solutions is the leading provider of light, electron, X-ray microscope systems, correlative microscopy and software solutions leveraging AI technologies. The portfolio comprises of products and services for life sciences, materials and industrial research, as well as education and clinical routine applications. The unit is headquartered in Jena. Additional production and development sites are located in Germany, UK, USA and China. ZEISS Research Microscopy Solutions is part of the Industrial Quality & Research segment.

Further information at www.zeiss.com/microscopy

Press photos

Organoid

The figure displays a cross-sectional view of an intestinal gut organoid captured at 20X magnification on ZEISS Celldiscoverer 7 and segmented using ZEISS arivis Pro image analysis software. The image highlights outer cell layer nuclei in pink and the inner luminal nuclei in yellow.

File size: 472 KB

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ZEISS arivis Pro 4.2

3D volume rendering of segmented mouse muscle ultrastructure overlaid on the original EM data. The rendering visualizes the segmented components of the muscle tissue, including filaments (green), capillary (yellow), myofibrils (blue), mitochondria (cyan), and sarcoplasmic reticulum (pink), in their native 3D context within the EM volume.

File size: 258 KB

Download