ZEISS Celldiscoverer 7

Live cell imaging requires objectives with high numerical apertures. Those objectives will only deliver high contrast and sensitivity if their optics can adapt to variations in bottom thickness or to the material of different sample carriers. You are free to use Petri dishes, chamber slides, multi-well plates, plastic or glass, thin or thick vessel bottoms, low-skirt or high-skirt plates. Automatic sample recognition detects all relevant vessel features while loading your sample. Autocorr adjusts the correction ring of the objective to compensate for spherical aberrations.

In cell biology or screening applications, your samples mostly consist of water and / or will be mounted in aqueous solutions. Celldiscoverer 7 combines an outstanding 50x water immersion objective with rapid automated immersion supply and removal. An elastic silicon membrane simultaneously seals the sample chamber to avoid unnecessary airflow while protecting the system from potential liquid spillage. You can perform unbiased live cell experiments at 37 °C over several days or carry out extensive scanning processes on multi-well plates.

Use the hardware-based Find Focus function to automatically focus your sample and find your region of interest quickly with just a single click. Select Definite Focus to maintain the focal position throughout your live cell experiment, whether it takes a few seconds or several days. Or combine both methods: Celldiscoverer 7 can automatically create focus maps for multiple positions in long-term time-lapse experiments.

The Adaptive Lens Guard protects the objective from collisions with your sample vessel or hardware components, automatically maximizing the available scanning area. Sample carrier holders are designed so that the entire sample can be imaged even at maximum magnification, e.g., in chamber slides.

Celldiscoverer 7 brings you all the advantages of LED technology for efficient widefield illumination with low phototoxicity, fast switching times and homogeneous illumination. Real-time and long-term stabilization with performance optimization ensure comparability of images. The LED module includes up to 7 individually controlled excitation lines for maximum flexibility in the choice of dyes, from deep blue to far red. You always get enough excitation power to shorten exposure times and to speed up your image acquisition.

Life happens in 3D. Add LSM 900 with Airyscan 2 and get the best of both worlds: ease of use and automation from a fully integrated microscope platform and the superb confocal image quality and flexibility of LSM 9 family. Super-resolution 3D imaging with up to 1.9x resolution improvement becomes possible. Easily separate multiple labels with spectral imaging. Analyze dynamic processes in living samples with photomanipulation for FRAP, FRET or related techniques. Precisely connect widefield and confocal images. Fast mixed-mode acquisition simplifies and speeds up your workflow and gives you unique insights into your sample.