Scalable image analysis to shorten time to results. Graphic representation of the image analysis journey from left to right. Images are created and stored in diverse equipment. The images are analyzed with automated workflows. Then all images and workflows can be sent into a central hub for processing and batch analysis that scaled up to thousand of images, for faster reproducible results.
Profile image of Dr. Sreenivas Bhattiprolu
Author Sreenivas Bhattiprolu Ph.D. Head of Digital Solutions

ZEISS arivis

User Story

Scalable Image Analysis for Biotech and Pharma

How ZEISS arivis Hub Can Help Transform Biotech & Pharma Research.

In the realm of biotech and pharma research, the journey from hypothesis to breakthrough is paved with massive experiments. These experiments, often involving complex microscopy techniques, generate large multidimensional data. Analyzing this data is a crucial step in the innovation of new therapies that have the potential to save human lives. However, legacy systems, with their outdated operating systems and inflexible tools, can slow down this process significantly. Enter ZEISS arivis Hub, a state-of-the-art image analysis solution designed to revolutionize the way researchers interact with their data.

Large-scale data processing

Revolutionizing Research Data Handling

Designed for Scalable Image Analysis and Storage

ZEISS arivis Hub is built to handle the scale and complexity of modern research data. It enables the design and execution of large-scale experiments, allowing for efficient processing of large microscopy data. Our software enables scaling up and down of analysis processing resources providing faster turnaround times.

In our scalable approach, illustrated in the accompanying graphic, you'll see how multiple high-capacity processors, each equivalent to 16 cores, work collaboratively like a well-coordinated team. This ensures the swift and parallel processing of your experiments, optimizing efficiency.

Researchers can create analysis pipelines in ZEISS arivis Pro and upload them onto ZEISS arivis Hub once vetted to be used by others.

Access from Anywhere

In today’s interconnected world, research is no longer confined to the lab. ZEISS arivis Hub can be accessed from anywhere, enabling multi-user remote access to the system. Whether you’re working from the lab, your home, or halfway across the world, ZEISS arivis Hub keeps you connected to your data.

Works with Many File Formats

ZEISS arivis Hub offers flexibility to seamlessly work with various imaging systems found in any laboratory setting. Whether your microscopy data originates from a ZEISS system or a non-Zeiss system such as Yokogawa or Opera Phenix, ZEISS arivis Hub seamlessly accommodates many file formats. This flexibility is especially valuable for labs that work with various types of imaging equipment, as it allows for the smooth integration of ZEISS arivis Hub into your existing workflows.

A Screenshot of the ZEISS arivis Hub software. A slice of organoid microscopy image is seen while some indicators on the screen show the processing is running.
A Screenshot of the ZEISS arivis Hub software. A slice of organoid microscopy image is seen while some indicators on the screen show the processing is running.

Visualization of multidimensional organoids that are ready for scaled analysis.

Visualization of multidimensional organoids that are ready for scaled analysis.

Automated Analysis and Enhanced Visualization

Multidimensional Visualization and Analysis

ZEISS arivis Hub offers multidimensional visualization and analysis of images of any size, without the need for local hardware requirements. From small to very large datasets, ZEISS arivis Hub handles visualization effortlessly, providing you with the insights you need to drive your research forward. Whether you’re dealing with flat 2D cell cultures, intricate 3D organoids, or dynamic 4D time-lapse microscopy, ZEISS arivis Hub has got you covered for your visualization and image analysis needs.

AI-ready for Image Analysis

ZEISS arivis Hub is AI-ready, allowing for the execution of preconfigured AI-powered image analysis pipelines at scale. It supports a large range of image analysis algorithms, including segmentation algorithms based on traditional tools (e.g., blob detection), conventional machine learning (e.g., Random Forest), pre-trained deep learning open-source models (e.g., Cellpose), and customizable deep learning models (e.g., ZEISS arivis Cloud).

ZEISS arivis Hub
ZEISS arivis Hub

A screenshot of ZEISS arivis Hub showing an AI-powered image analysis pipeline specifically designed for fiber analysis.

A screenshot of ZEISS arivis Hub showing an AI-powered image analysis pipeline specifically designed for fiber analysis.

Run Tailored Pipelines at Scale

User-Friendly and Intuitive

ZEISS arivis Hub offers the ability to securely import and store data, utilizing these datasets in personalized pipelines enhanced by artificial intelligence. You can tailor these pipelines using the ZEISS arivis Pro image analysis software, and scale them for optimal throughput using ZEISS arivis Hub.

ZEISS arivis Hub is not only versatile but also user-friendly. Its intuitive interface ensures that any member of your team, regardless of their technical skills, can get started without wasting time trying to figure out how to use the software.

Comprehensive Image Analysis for Diverse Cellular Assays

ZEISS arivis Hub is not just flexible; it's comprehensive. It supports automated image analysis for a wide range of cellular assays. Whether you're studying cell proliferation, analyzing neurite outgrowth, or exploring 3D organoid analysis, ZEISS arivis Hub has got you covered.

  • Our software can handle various tasks including but not limited to:

    • Apoptosis
    • Cell Cycle
    • Cell Differentiation
    • Cell Migration
    • Cell Proliferation
    • Cell Shape Changes
    • Cytoskeletal Rearrangement
    • Cytotoxicity
    • Infection/Infiltration Rates
    • Lipid Droplet Analysis
    • Neurite Outgrowth
    • Protein Expression
    • Receptor Activation
    • Reporter Gene
    • Signaling Pathway Analysis
    • Transcription Factors
    • 3D Cell Model Imaging and Analysis
    • Live-cell Imaging and Analysis
    • 2D and 3D Organoid Analysis
    • High Content Analysis (HCA)
    • etc.
Dr. Sreenivas Bhattiprolu

Scalable image analysis is a crucial step in the innovation of new therapies that have the potential to save human lives.

 

ZEISS arivis Hub is built to handle the scale and complexity of modern research data. It enables the design and execution of large-scale experiments, allowing for efficient processing of large microscopy data.

Sreenivas Bhattiprolu Ph.D. Head of Digital Solutions (ZEISS arivis)
Representative clip of data set with identified objects as bounding boxes
Representative clip of data set with identified objects as bounding boxes

High Content Imaging and Analysis for Genotoxicity

In this case study, we set up an application example to perform DNA-damage analysis by employing ZEISS Axio Observer and the ZEISS arivis Pro image analysis software.

Future-Proof on a Modern Operating System

Safety, Security, and Support

At ZEISS, we understand that your data is invaluable. That's why data safety and security are our utmost priorities. You can rest assured that your data is protected, whether you're leveraging computation onsite or offsite. No more concerns about data loss when a user transitions out; your local administrator can access all your data, including the analyses performed.

ZEISS arivis Hub is designed to be future-proof, operating on a modern operating system that frees you from the constraints of outdated software. This modern system enables image analysis at scale, offering support for multiple CPUs and GPUs to analyse large datasets. With ZEISS arivis Hub, you're not just keeping up with the times; you're staying ahead of them.

High content organoid analysis illustration. On the right a large image containing many organoids is fed into ZEISS arivis Hub and the diverse organoids (approx. 100) are analyzed in parallel. On the left you see results of enhanced 3D analysis of individual organoids.

3D Organoid Analysis: For more information on this application, please refer to our case study.

Easy Server Installation

Excellent Technical Support

Whether you opt for a cloud setup or choose to install the server locally on your premises, our team of experts can collaborate with your IT department to swiftly initiate your journey with ZEISS arivis Hub. In many cases, the on-premises installation can be completed in just one working day.

At ZEISS, we believe in supporting our users every step of the way. Our team is always ready to assist you, ensuring you can focus on what matters most - your research.

Conclusion

These capabilities make ZEISS arivis Hub a versatile tool for researchers working on diverse topics. With ZEISS arivis Hub, you can tailor your image analysis pipelines to suit your specific research needs, making it an invaluable tool in your research arsenal. Whether you're a seasoned researcher or a novice in the field, ZEISS arivis Hub's user-friendly and intuitive interface ensures that you can get started without wasting time trying to figure out how to use the software. And if you ever need help, our excellent technical support team is always ready to assist you. With ZEISS arivis Hub, the possibilities are endless. Are you ready to take your image analysis to the next level? Step into the future of image analysis with us and let's innovate together.


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