Aplicaciones de microscopía para medicina reproductiva
Soluciones de microscopía para calidad del embrión
Indicadores de un embrión de «buena calidad»
Tras la fecundación del ovocito, se monitoriza el crecimiento del embrión hasta su implantación. Los embriólogos han desarrollado parámetros morfológicos que indican un buen o mal pronóstico para el embrión en desarrollo. Cada paso del desarrollo se observa detenidamente.
Algunos indicadores de un embrión de «buena calidad» son:
Número de células: blastómeros y embrión de 3 días
Regularidad de las células
Fragmentación/vesiculación
Multinucleación
Presencia de vacuolas, granularidad, grosor de la membrana externa (o zona pelúcida)
Ejemplos de aplicación
Cortesía del Dr. L. M. Criado Rodríguez, Departamento de transgénesis, Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, España
Núcleos con nucléolos visibles en la célula iHMC derecha
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![Embriones de ratón transgénicos en DIC, cortesía del Dr. L. M. Criado Rodríguez, Departamento de transgénesis, Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, España]({"xsmall":"https://www.zeiss.com/content/dam/rms/reference-master/applications/reproductive-medicine/plasdic_mouseembryo_micromanipulation_2.jpg/_jcr_content/renditions/original.image_file.100.75.4,0,1388,1038.file/plasdic_mouseembryo_micromanipulation_2.jpg","small":"https://www.zeiss.com/content/dam/rms/reference-master/applications/reproductive-medicine/plasdic_mouseembryo_micromanipulation_2.jpg/_jcr_content/renditions/original.image_file.360.270.4,0,1388,1038.file/plasdic_mouseembryo_micromanipulation_2.jpg","medium":"https://www.zeiss.com/content/dam/rms/reference-master/applications/reproductive-medicine/plasdic_mouseembryo_micromanipulation_2.jpg/_jcr_content/renditions/original.image_file.768.576.4,0,1388,1038.file/plasdic_mouseembryo_micromanipulation_2.jpg","large":"https://www.zeiss.com/content/dam/rms/reference-master/applications/reproductive-medicine/plasdic_mouseembryo_micromanipulation_2.jpg/_jcr_content/renditions/original.image_file.1024.768.4,0,1388,1038.file/plasdic_mouseembryo_micromanipulation_2.jpg","xlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/reproductive-medicine/plasdic_mouseembryo_micromanipulation_2.jpg/_jcr_content/renditions/original.image_file.1280.960.4,0,1388,1038.file/plasdic_mouseembryo_micromanipulation_2.jpg","xxlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/reproductive-medicine/plasdic_mouseembryo_micromanipulation_2.jpg/_jcr_content/renditions/original.image_file.1384.1038.4,0,1388,1038.file/plasdic_mouseembryo_micromanipulation_2.jpg","max":"https://www.zeiss.com/content/dam/rms/reference-master/applications/reproductive-medicine/plasdic_mouseembryo_micromanipulation_2.jpg/_jcr_content/renditions/original.image_file.1384.1038.4,0,1388,1038.file/plasdic_mouseembryo_micromanipulation_2.jpg"} "Embriones de ratón transgénicos en DIC, cortesía del Dr. L. M. Criado Rodríguez, Departamento de transgénesis, Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, España")
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