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Courtesy: K.S. Okuda, Peter MacCallum Cancer Centre, Australia
Use Case

Zebrafish Research

Dive into the Dynamic World of Zebrafish Research!
Discover the vibrant world of zebrafish research with our state-of-the-art microscopy solutions. Unlock unparalleled insights into developmental biology, genetics, and disease models. Elevate your research today.
 

Model Systems in Life Science Research

Unveiling Zebrafish Research Potential
  • zebrafish
  • zebrafish
  • zebrafish
  • zebrafish
    zebrafish
    ] Copyright needs to be added: Courtesy of the Fish Facility, Leibniz Institute on Aging - Fritz Lipmann Institute e.V., Germany
    ] Copyright needs to be added: Courtesy of the Fish Facility, Leibniz Institute on Aging - Fritz Lipmann Institute e.V., Germany
  • zebrafish
    zebrafish
  • zebrafish Sample courtesy of B. Schmid, DZNE Munich, Germany
    zebrafish Sample courtesy of B. Schmid, DZNE Munich, Germany
    Sample courtesy of B. Schmid, DZNE Munich, Germany
    Sample courtesy of B. Schmid, DZNE Munich, Germany

Zebrafish: The Transparent Catalyst in Life Science Breakthroughs

The use of zebrafish (Danio rerio) as a model organism has significantly advanced our understanding of developmental biology, genetics, pharmacology, and the mechanisms of disease. This vertebrate offers a unique combination of genetic similarity to humans, transparency during early development, and the ease of genetic manipulation.

Our microscopy technologies, including the Stemi 305, Axiovert 5, and Primovert, are at the forefront of this research, providing detailed, live imaging capabilities that reveal cellular and molecular processes in real-time. These tools enable researchers to observe the effects of genetic modifications, drug treatments, and environmental changes on zebrafish development and health. Moreover, our Labscope software enhances data analysis, allowing for the integration of imaging findings with genetic and biochemical data.

This synergy between advanced microscopy and the versatile zebrafish model paves the way for breakthroughs in understanding human diseases and developing new therapies. Our commitment to innovation ensures that researchers have the most sophisticated tools at their disposal to explore the complexities of life, making every discovery possible.

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Unveiling the Potential of Zebrafish in Life Science Innovation with our new solutions.
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Microscopy & Zebrafish

The Lightsheet 7
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Light-Sheet Multiview Imaging of Living and Cleared Specimens

ZEISS LSM 900 and LSM 980 microscopes play an essential role, enhancing our understanding of complex biological processes. From studying microglia's role in brain development to observing vascular formation, ZEISS’s cutting-edge technology , provides unparalleled imaging capabilities. These instruments allow researchers to conduct detailed material analyses and live imaging with minimal phototoxicity. The ZEISS Lightsheet 7, for example, is perfect for extended imaging sessions of living organisms, allowing observations with exceptional clarity and speed. The Axio Observer merges high-resolution imaging with user-friendly automation, streamlining the research workflow and enhancing productivity.
 

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Focal Adhesion in Vivo

Focal Adhesion In Vivo

with Dr. Minna Roh-Johnson

Understanding how melanoma cells migrate requires in vivo study.

Central to the issue is focal adhesion, or how cancer cells attach to an underlying substrate. Despite years of research, the organization of these structures is still unclear.

Zebrafish earn their stripes

Dr. Roh-Johnson’s lab has developed an innovative system in zebrafish larvae that allows them to observe the formation of focal adhesion structures in highly migratory melanoma cells on the surface of the skin.

Tracking melanoma in zebrafish

They have used this system to dissect the composition and dynamics of focal adhesion structures and have identified unique properties of cancer cells in their native environments. This deeper understanding of focal adhesion formation is a positive step toward therapies to prevent it.

Model Systems in Life Science Articles