![用于神经病理学的显微镜解决方案 用于神经病理学的显微镜解决方案]({"xsmall":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.100.100.0,0,1080,1080.file/24-a-tumor-core.jpg","small":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.360.360.0,0,1080,1080.file/24-a-tumor-core.jpg","medium":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.768.768.0,0,1080,1080.file/24-a-tumor-core.jpg","large":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.1024.1024.0,0,1080,1080.file/24-a-tumor-core.jpg","xlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.1080.1080.0,0,1080,1080.file/24-a-tumor-core.jpg","xxlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.1080.1080.0,0,1080,1080.file/24-a-tumor-core.jpg","max":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.1080.1080.0,0,1080,1080.file/24-a-tumor-core.jpg"})
适合您实验室的显微镜应用
用于神经病理学的显微镜解决方案
大脑和神经系统疾病的诊断与研究
神经病理学是病理学的一个分支,主要关注大脑和神经系统疾病的诊断与研究。诊断对于个体患者治疗或法医鉴定请求十分必要,并且通常基于对神经外科提取的组织样品进行的显微镜和分子分析。常见研究领域包括中枢神经系统(CNS)内的肿瘤和疾病,如胶质母细胞瘤、神经退行性变化和各种脑发育障碍。
作为内科医生,神经病理学家在患者(如脑肿瘤患者)的治疗方面发挥着重要作用,因为神经病理学分析结果是促进诊断的关键因素。做出诊断后,神经外科医生和神经肿瘤学家会在癌症病例讨论会上共同决定个性化治疗方案。
在神经外科中,使用造影剂的成像技术越来越多地用于改善术中决策。1 通常,成像系统旨在使荧光区域宏观可视化,并依赖于配备了适当滤光片和光源的手术显微镜。1对于共聚焦显微内镜(CEM)2 ,该技术经过改进,可在高放大倍率下观察组织的微观结构。它提供实时和体内成像,即无需提取组织。1 在CEM中,类似于刚性内窥镜的扫描探针轻触组织表面,基于荧光剂揭示亚表面级细胞和结构细节。1
了解更多有关共聚焦显微图像分析的信息
体内 和实时
使用静脉注射荧光素钠在小鼠体内进行神经胶质瘤实验(体内)。
图像由Mark C. Preul博士和Evgenii Belykh博士(巴罗神经研究所神经外科研究实验室)提供
![匹配的CONVIVO图像 匹配的CONVIVO图像]({"xsmall":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core-sequence-contrast-enhanced.jpg/_jcr_content/renditions/original.image_file.100.75.240,0,1680,1080.file/24-a-tumor-core-sequence-contrast-enhanced.jpg","small":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core-sequence-contrast-enhanced.jpg/_jcr_content/renditions/original.image_file.360.270.240,0,1680,1080.file/24-a-tumor-core-sequence-contrast-enhanced.jpg","medium":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core-sequence-contrast-enhanced.jpg/_jcr_content/renditions/original.image_file.768.576.240,0,1680,1080.file/24-a-tumor-core-sequence-contrast-enhanced.jpg","large":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core-sequence-contrast-enhanced.jpg/_jcr_content/renditions/original.image_file.1024.768.240,0,1680,1080.file/24-a-tumor-core-sequence-contrast-enhanced.jpg","xlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core-sequence-contrast-enhanced.jpg/_jcr_content/renditions/original.image_file.1280.960.240,0,1680,1080.file/24-a-tumor-core-sequence-contrast-enhanced.jpg","xxlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core-sequence-contrast-enhanced.jpg/_jcr_content/renditions/original.image_file.1440.1080.240,0,1680,1080.file/24-a-tumor-core-sequence-contrast-enhanced.jpg","max":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core-sequence-contrast-enhanced.jpg/_jcr_content/renditions/original.image_file.1440.1080.240,0,1680,1080.file/24-a-tumor-core-sequence-contrast-enhanced.jpg"})
图像由Mark C. Preul博士和Evgenii Belykh博士(巴罗神经研究所神经外科研究实验室)提供
![H&E染色切片 H&E染色切片]({"xsmall":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.100.75.240,0,1681,1081.file/24-a-tumor-core.jpg","small":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.360.270.240,0,1681,1081.file/24-a-tumor-core.jpg","medium":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.768.576.240,0,1681,1081.file/24-a-tumor-core.jpg","large":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.1024.768.240,0,1681,1081.file/24-a-tumor-core.jpg","xlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.1280.960.240,0,1681,1081.file/24-a-tumor-core.jpg","xxlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.1440.1080.240,0,1681,1081.file/24-a-tumor-core.jpg","max":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/neuropathology/24-a-tumor-core.jpg/_jcr_content/renditions/original.image_file.1441.1081.240,0,1681,1081.file/24-a-tumor-core.jpg"})
-
1
1) Leierseder S. Confocal Endomicroscopy during brain surgery.Laser+Phtonics 2018.
来源:https://www.photonik.de/confocal-endomicroscopy-during-brain-surgery/150/21404/363684 [访问日期:2020年4月2日]。
2) 常用的等效表达是“共聚焦激光显微内镜”(CLE)。